Case Report

Erythrocytosis and fatigue fractures associated with hepatoblastoma in a 3-year-old gelding

Sharon Tirosh-Levy, Shmuel Perl, Beth A. Valentine, Gal Kelmer
Journal of the South African Veterinary Association | Vol 90 | a1708 | DOI: https://doi.org/10.4102/jsava.v90i0.1708 | © 2019 Sharon Tirosh-Levy, Shmuel Perl, Beth A. Valentine, Gal Kelmer | This work is licensed under CC Attribution 4.0
Submitted: 18 June 2018 | Published: 28 March 2019

About the author(s)

Sharon Tirosh-Levy, Department of Large Animal Surgery, Veterinary Teaching Hospital, Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
Shmuel Perl, Department of Pathology, Kimron Veterinary Institute, Bet-Dagan, Israel
Beth A. Valentine, Department of Anatomic Pathology, College of Veterinary Medicine, Oregon State University, Corvallis, United States
Gal Kelmer, Department of Large Animal Surgery, Veterinary Teaching Hospital, Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel


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Abstract

Hepatoblastoma was diagnosed in a 3-year-old Thoroughbred gelding presented with forelimb lameness with bilateral fatigue fractures of the proximal third metacarpal bones. An abdominal mass was detected on ultrasound examination of the abdomen. Absolute erythrocytosis was diagnosed after clinical and haematological evaluation. The fractured metacarpal bones were surgically removed but complications after surgery were fatal. The liver mass was diagnosed as a hepatoblastoma based on histology and immunochemical staining. The combination of hepatoblastoma and fatigue fractures has not been described previously in horses. A potential link between the hepatic and orthopaedic pathologies is hypothesised.


Keywords

equine; erythrocytosis; hepatoblastoma; fatigue fracture

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