The efficacy of a slow-release albendazole capsule against Haemonchus contortus with known resistance to albendazole

Authors

  • Alan D Fisher Provincial Veterinary Laboratory
  • Sybrand J van Sittert MSD Malelane Research Unit

Abstract

Controlled-release albendazole capsules (CRCs) are currently registered for use in Australia and New Zealand as anthelmintic treatment in sheep. However, reports on the efficacy of such products on resistant parasite populations are sometimes controversial. This is the first study to report on the efficacy of such products under South African field conditions in sheep harbouring a population of Haemonchus contortus with known multiple anthelmintic resistance, including to albendazole. Treatment groups were comprised of CRC-treated and single dose albendazole-treated sheep, as well as negative controls. Groups were compared by using faecal egg count reduction tests, FAMACHA© anaemia scoring, conception rates and comparative weight gains over three and a half months. Based on a comparison of faecal egg counts, no advantage could be found using CRCs. Moreover, the use of the product actually decreased weight gain when compared with the control group animals.

Author Biographies

  • Alan D Fisher, Provincial Veterinary Laboratory

    Eastern Cape Department of Rural Development and Agrarian Reform, Provincial Veterinary Laboratory,
    Queenstown, South Africa

  • Sybrand J van Sittert, MSD Malelane Research Unit

    MSD Malelane Research Unit, Malelane, South Africa

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Published

2021-12-06

Issue

Vol. 84 No. 1 (2013)

Section

Original Research