Original Research

Phylogenetic analysis to define feline immunodeficiency virus subtypes in 31 domestic cats in South Africa

R. Kann, J. Seddon, M. Kyaw-Tanner, J.P. Schoeman, T. Schoeman, J. Meers
Journal of the South African Veterinary Association | Vol 77, No 3 | a356 | DOI: https://doi.org/10.4102/jsava.v77i3.356 | © 2006 R. Kann, J. Seddon, M. Kyaw-Tanner, J.P. Schoeman, T. Schoeman, J. Meers | This work is licensed under CC Attribution 4.0
Submitted: 08 June 2006 | Published: 08 June 2006

About the author(s)

R. Kann,
J. Seddon,
M. Kyaw-Tanner,
J.P. Schoeman,
T. Schoeman,
J. Meers,

Full Text:

PDF (200KB)

Share this article

Bookmark and Share

Abstract

Feline immunodeficiency virus (FIV), a lentivirus, is an important pathogen of domestic cats around the world and has many similarities to human immunodeficiency virus (HIV). A characteristic of these lentiviruses is their extensive genetic diversity, which has been an obstacle in the development of successful vaccines. Of the FIV genes, the envelope gene is the most variable and sequence differences in a portion of this gene have been used to define 5 FIV subtypes (A, B, C, D and E). In this study, the proviral DNA sequence of the V3-V5 region of the envelope gene was determined in blood samples from 31 FIV positive cats from 4 different regions of South Africa. Phylogenetic analysis demonstrated the presence of both subtypes A and C, with subtype A predominating. These findings contribute to the understanding of the genetic diversity of FIV.

Keywords

Domestic Cats; Feline Immunodeficiency Virus; Subtypes; Phylogenetic Analysis; South Africa

Metrics

Total abstract views: 1583
Total article views: 2100

 

Crossref Citations

1. South African report of first case of chromoblastomycosis caused by Cladosporium (syn Cladophialophora) carrionii infection in a cat with feline immunodeficiency virus and lymphosarcoma
Anthony B Zambelli, Catherine A Griffiths
Journal of Feline Medicine and Surgery  vol: 17  issue: 4  first page: 375  year: 2015  
doi: 10.1177/1098612X14559954