Original Research

Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)

K. E. Joubert, T. Serfontein, M. Scantlebury, M B Manjerovic, P. W. Bateman, M B Manjerovic, P. W. Bateman, N. C. Bennett, J. M. Waterman
Journal of the South African Veterinary Association | Vol 82, No 2 | a41 | DOI: https://doi.org/10.4102/jsava.v82i2.41 | © 2011 K. E. Joubert, T. Serfontein, M. Scantlebury, M B Manjerovic, P. W. Bateman, M B Manjerovic, P. W. Bateman, N. C. Bennett, J. M. Waterman | This work is licensed under CC Attribution 4.0
Submitted: 10 April 2011 | Published: 11 April 2011

About the author(s)

K. E. Joubert, Pharmacology, Department of Paraclinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa., South Africa
T. Serfontein, Anaesthesiology, Onderstepoort Academic Veterinary Hospital, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa., South Africa
M. Scantlebury, School of Biological Sciences, Queen’s University Belfast, Belfast BT9 7BL, UK. Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
M B Manjerovic, Department of Biology, University of Central Florida, Orlando, FL 32816-2368, USA., United States
P. W. Bateman, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa, South Africa
M B Manjerovic, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa, South Africa
P. W. Bateman, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
N. C. Bennett, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
J. M. Waterman, Department of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Canada

Full Text:

PDF (165KB)

Share this article

Bookmark and Share

Abstract

The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effects of medetomidine. The mean dose of medetomidine was 67.6±9.2 μg/kg, ketamine 13.6±1.9 mg/kg and buprenorphine 0.5±0.06 μg/kg. Induction time was 3.1 ± 1.4 min. This produced surgical anaesthesia for 21± 4.2 min. Atipamezole 232±92 μg/kg produced a rapid recovery. Squirrels were sternally recumbent in 3.5 ± 2.2 min.

Keywords

No related keywords in the metadata.

Metrics

Total abstract views: 2765
Total article views: 3251


Crossref Citations

No related citations found.