Erythrocytosis and fatigue fractures associated with hepatoblastoma in a 3-year-old gelding

Authors

  • Sharon Tirosh-Levy The Hebrew University of Jerusalem
  • Shmuel Perl Kimron Veterinary Institute
  • Beth A Valentine Oregon State University
  • Gal Kelmer The Hebrew University of Jerusalem

Abstract

Hepatoblastoma was diagnosed in a 3-year-old Thoroughbred gelding presented with forelimb lameness with bilateral fatigue fractures of the proximal third metacarpal bones. An abdominal mass was detected on ultrasound examination of the abdomen. Absolute  erythrocytosis was diagnosed after clinical and haematological evaluation. The fractured metacarpal bones were surgically removed but complications after surgery were fatal. The liver mass was diagnosed as a hepatoblastoma based on histology and immunochemical staining. The combination of hepatoblastoma and fatigue fractures has not been described
previously in horses. A potential link between the hepatic and orthopaedic pathologies is hypothesised.
Keywords: equine; erythrocytosis; hepatoblastoma; fatigue fracture.

Author Biographies

  • Sharon Tirosh-Levy, The Hebrew University of Jerusalem

    Department of Large Animal Surgery, Veterinary Teaching Hospital, Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel

  • Shmuel Perl, Kimron Veterinary Institute

    Department of Pathology, Kimron Veterinary Institute, Bet-Dagan, Israel

  • Beth A Valentine, Oregon State University

    Department of Anatomic Pathology, College of Veterinary Medicine, Oregon State University, Corvallis,
    United States

  • Gal Kelmer, The Hebrew University of Jerusalem

    Department of Large Animal Surgery, Veterinary Teaching Hospital, Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel

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Published

2021-12-09

Issue

Section

Case Report