Case Report

Temporary remission of disseminated paecilomycosis in a German shepherd dog treated with ketoconazole : case report

M.J. Booth, J.J. Van der Lugt, A. Van Heerden, J.A. Picard
Journal of the South African Veterinary Association | Vol 72, No 2 | a628 | DOI: https://doi.org/10.4102/jsava.v72i2.628 | © 2001 M.J. Booth, J.J. Van der Lugt, A. Van Heerden, J.A. Picard | This work is licensed under CC Attribution 4.0
Submitted: 09 July 2001 | Published: 09 July 2001

About the author(s)

M.J. Booth,
J.J. Van der Lugt,
A. Van Heerden,
J.A. Picard,

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Abstract

Disseminated mycosis caused by Paecilomyces varioti in a female German shepherd dog presented with chronic forelimb lameness is described. Radiographs of the swollen carpal joint revealed geographic lysis of the radial epiphysis. Diagnosis was based on cytological demonstration of fungal hyphae and chlamydiospores, as well as fungal culture of fluid obtained by arthrocentesis. Temporary remission was characterised by markedly improved clinical signs and laboratory parameters, following treatment with ketoconazole. The dog was euthanased 9 months after the initial diagnosis, following the diagnosis of multifocal discospondylitis. This appears to be the longest described period of temporary remission obtained with treatment in dogs with paecilomycosis. Clinical, clinicopathological and necropsy findings of this disease in another German shepherd dog are briefly described.

Keywords

Arthritis; Discospondylitis; German Shepherd Dog; Hyalohyphomycosis; Paecilomyces Varioti; Ketoconazole; Osteomyelitis

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Crossref Citations

1. Sequential opportunistic infections in two German Shepherd dogs
MB Krockenberger, G Swinney, P Martin, TRL Rothwell, R Malik
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doi: 10.1111/j.1751-0813.2010.00666.x