Original Research

A krimpsiekte-like syndrome in small stock poisoned by Ornithogalum toxicarium Archer & Archer

C.J. Botha, R.A. Schultz, J.J. Van der Lugt, C. Archer
Journal of the South African Veterinary Association | Vol 71, No 1 | a668 | DOI: https://doi.org/10.4102/jsava.v71i1.668 | © 2000 C.J. Botha, R.A. Schultz, J.J. Van der Lugt, C. Archer | This work is licensed under CC Attribution 4.0
Submitted: 09 July 2000 | Published: 10 July 2000

About the author(s)

C.J. Botha,
R.A. Schultz,
J.J. Van der Lugt,
C. Archer,

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Abstract

Krimpsiekte (the syndrome associated with chronic cardiac glycoside poisoning) was purportedly induced by Ornithogalum toxicarium in the Karas mountains area of Keetmanshoop, Namibia. This chinkerinchee species was previously linked to a condition known as 'kwylbek' krimpsiekte in small stock in the Beaufort West district of the Western Cape Province, South Africa. In a dosing trial, respiratory distress, tachycardia and sternal recumbency were observed in 2 sheep drenched with fresh plant material. A fluorescence polarisation immunoassay (FPIA) detected the presence of a substance that cross-reacted with digoxin antibodies in some of the plant material collected at Keetmanshoop and Beaufort West. This is the first time that apparent cardiac glycoside poisoning was induced by a southern African chinkerinchee species. The presence of the cardiac glycoside-like substance in O. toxicarium requires further chemical verification.

Keywords

Cardiac Glycoside Poisoning; Chinkerinchee; Goats; Krimpsiekte; Ornithogalum; Sheep

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