Short Communication

Screening of five drugs for efficacy against Babesia felis in experimentally infected cats : research communication

B.L. Penzhorn, B.D. Lewis, L.M. López-Rebollar, G.E. Swan
Journal of the South African Veterinary Association | Vol 71, No 1 | a678 | DOI: https://doi.org/10.4102/jsava.v71i1.678 | © 2000 B.L. Penzhorn, B.D. Lewis, L.M. López-Rebollar, G.E. Swan | This work is licensed under CC Attribution 4.0
Submitted: 10 July 2000 | Published: 10 July 2000

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B.L. Penzhorn,
B.D. Lewis,
L.M. López-Rebollar,
G.E. Swan,

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Abstract

The efficacy of 5 drugs was tested against experimental Babesia felis infection in domestic cats. Two of the drugs, rifampicin and a sulphadiazine-trimethoprim combination, appeared to have an anti-parasitic effect, but were inferior to primaquine. The other 3 drugs, buparvaquone, enrofloxacin and danofloxacin, had no significant anti-babesial effect.

Keywords

Babesia Felis; Buparvaquone; Cats; Chemotherapy; Danofloxacin; Enrofloxacin; Primaquine; Sulphadiazine; Trimethoprim

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